Friday, April 15, 2011


If you're curious about helping the cause to research further into Mesothelioma or just have more questions, go to


The prognosis for malignant mesothelioma remains disappointing, although there have been some modest improvements in prognosis from newer chemotherapies and multimodality treatments. Treatment of malignant mesothelioma at earlier stages has a better prognosis, but cures are exceedingly rare. Clinical behavior of the malignancy is affected by several factors including the continuous mesothelial surface of the pleural cavity which favors local metastasis via exfoliated cells, invasion to underlying tissue and other organs within the pleural cavity, and the extremely long latency period between asbestos exposure and development of the disease. The histological subtype and the patient's age and health status also help predict prognosis.


Working with asbestos is the major risk factor for mesothelioma. In the United States, asbestos is the major cause of malignant mesothelioma and has been considered "indisputably" associated with the development of mesothelioma. Indeed, the relationship between asbestos and mesothelioma is so strong that many consider mesothelioma a “signal” or “sentinel” tumor.

Symptoms of Mesothelioma

Symptoms include:

  • Chest wall pain

  • Pleural effusion, or fluid surrounding the lung

  • Shortness of breath

  • Fatigue or anemia

  • Wheezing, hoarseness, or cough

  • Blood in the sputum (fluid) coughed up (hemoptysis)

  • Blood clots in the veins, which may cause thrombophlebitis

  • Disseminated intravascular coagulation, a disorder causing severe bleeding in many body organs

  • Jaundice, or yellowing of the eyes and skin

  • Low blood sugar level

  • Pleural effusion

  • Pulmonary emboli, or blood clots in the arteries of the lungs

  • Severe ascites
  • What is Mesothelioma?

    Mesothelioma is a rare form of cancer that develops from the protective lining that covers many of the body's internal organs, the mesothelium. It is usually caused by exposure to asbestos.